Current Sensing for High Voltage Application
High voltage current sensing/monitoring can be designed using LTC6101 op-amp. The following current sensing circuit is capable of measuring electrical current in 500 volts system. Here is the schematic diagram of the circuit:

Two external Mosfets is added to hold off the voltage, allows the LTC6101 to be connected to a very high potentials and measure the current flow. The output current from the op-amp, that is proportional to the sensed voltage at Rsense, flows through M1 and create a ground referenced output voltage. [Schematic diagram source: Linear Technology Application Notes]
Related posts:
Another Symmetric Power Supply Without Center Tapped Transformer
Autonomous Fast NiMH Battery Charger Using Single Chip IC
Signal Conditioning Circuit for KMI 15/x Rotation Speed Sensor
Black Light (UV Tube Lamp) Inverter
Avoiding Electrolysis For Water Level Detector Probes Using Alternating Current Detection